Chelsea can open up a six point advantage over champions Manchester City when the pair meet on Saturday.
Chelsea thrashed Spurs 3-0 last time out, with defenders Thiago Silva and Antonio Rudiger among the goals.
Reece James scored the winning penalty as they beat Aston Villa on penalties in the Carabao Cup midweek.
Manchester City recovered from a goal down to thrash Wycombe 6-1 in the same competition.
Last weekend they were held to a 0-0 draw at home to Southampton, registering just the one shot on target.
Premier League form: Chelsea W4 D1 L0; Manchester City W3 D1 L1
Premier League top scorers
Chelsea – Romelu Lukaku 3 goals
Manchester City – Ferran Torres 2 goals
Chelsea beat Manchester City three times in three different competitions last term, including the Champions League final.
Manchester City did win the league fixture at Stamford Bridge though, with Kevin de Bruyne among the scorers in a 3-1 win.
Last five Premier League meetings
Manchester City 1 Chelsea 2 – 08/05/21
Chelsea 1 Manchester City 3 – 03/01/21
Chelsea 2 Manchester City 1 – 25/06/20
Manchester City 2 Chelsea 1 – 23/11/19
Manchester City 6 Chelsea 0 – 10/02/19
Édouard Mendy has missed Chelsea’s last two matches; however Tuchel is confident he will start on Saturday.
Marcos Alonso will likely keep Ben Chilwell out of the XI again, whilst James and Ngolo Kante may be on the bench.
Aymeric Laporte, John Stones, Rodri and Ilkay Gundogan are all injury doubts for Manchester City.
Ferran Torres and Raheem Sterling appear to be vying for one spot in the front three.
Expected starting XI’s
Chelsea (3-4-3): Mendy; Christensen, Silva, Rudiger; Azpilicueta, Kovacic, Jorginho, Alonso; Havertz, Lukaku, Mount
Manchester City (4-3-3): Ederson; Walker, Dias, Ake, Cancelo; De Bruyne, Fernandinho, Foden; Jesus, Torres, Grealish
Chelsea have won three in a row against Manchester City and are narrow favourites here
Correct Score: 1-0
Chelsea won 1-0 in the Champions League final and the same scoreline is likely on Saturday
Anytime Goalscorer: Romelu Lukaku
Lukaku has four goals against Manchester City and he has made a very good start to his second Chelsea spell