Chelsea took advantage of surprise slip-ups from Manchester City and Liverpool last weekend to open up a lead at the top of the Premier League.
Reece James owners were laughing last time out with the defender returning a ridiculous 21 points thanks to his two goals in the 3-0 win at Newcastle United.
There are some harder to call games this weekend, including the Manchester derby, with City looking to increase the pressure on Ole Gunnar Solskjaer.
Elsewhere Brentford host the whipping boys Norwich City, whilst West Ham host Liverpool on Sunday.
Southampton vs. Aston Villa: Toni Livramento
Two sides in contrasting form meet in the Friday evening fixture as Southampton entertain an Aston Villa side who have lost four consecutive matches.
Toni Livramento has proven to be the best bargain pick this season with his 42 points only bettered by eight defenders.
The former Chelsea full-back has now risen to 4.5 and owners who got on him early will be laughing.
I wouldn’t expect many goals at St.Mary’s on Friday evening and Livramento looks a good bet.
Manchester United vs. Manchester City: Joao Cancelo
The injury sustained by Raphael Varane in the Champions League midweek is a real blow for the hosts and it could see them move away from the 3-5-2 system they changed to following the 5-0 defeat by Liverpool.
Manchester City probably won’t get five at Old Trafford like Liverpool did; however it’s hard to look past an away victory.
Joao Cancelo owners have been unlucky this term with the majority of his hauls coming in the Champions League.
He is probably due a Premier League return and there isn’t a sweeter place to do it than at the ground of their big rivals.
Brentford vs. Norwich City: Ivan Toney
Ivan Toney owners have patiently waited a return from the striker; however he has just two goals and two assists this season.
A home fixture against rock bottom Norwich City though is the perfect time for Toney to re-find his form.
Norwich have conceded a division high 25, including seven in their last away fixture and it feels like Toney owners may well be rewarded here.
Chelsea vs. Burnley: Ben Chilwell
The returns Chelsea’s defenders have put up their season are bordering on ridiculous and it was James’ turn last time to haul.
Despite starting just nine of the 20 league games between them, James and Ben Chilwell have combined returns of seven goals and two assists.
Both were rotated for the midweek Champions League ties and they are both expected to start on Saturday
As to who returns the greater, a coin flip is probably the best bet, but a slight preference to Chilwell here.
Crystal Palace vs. Wolves: Conor Gallagher
Crystal Palace continue to surprise and they put in their best display of the season last time out as they won 2-0 away to champions Manchester City.
Prior to the trip to the Etihad, Gallagher had just one assist in his last six matches; however the Chelsea loanee scored one and assisted the other.
With Palace’s fixtures starting to look favourable, now may well be a good time to pick the midfielder up.
Brighton vs. Newcastle United: Robert Sanchez
Brighton’s excellent season continued last time out as they recovered from two goals down to earn an impressive point at Anfield.
Despite the recent takeover, Newcastle remain without a win and face an uphill battle to remain in the Premier League.
They looked very abject in the 3-0 loss at home to Chelsea last weekend and you’d fancy the hosts to keep a clean sheet here.
Robert Sanchez has been one of the best budget keeper picks this season and he looks a good bet on Saturday.
Arsenal vs. Watford: Emile Smith-Rowe
Arsenal’s resurgance continued last week as they earned a surprise 2-0 win away at Leicester City.
Having returned just 10 points in his first five games, Emile Smith-Rowe has 39 in the last five, scoring three and providing two assists.
Bar an incredible 15 minutes away at Everton, Watford have looked poor since Claudio Ranieri’s appointment and a home win looks probable here.
Smith-Rowe remains very cheap and at 5.6 he is an excellent pick for this fixture.
Everton vs. Tottenham: Heung Min Son
In an eventful week for Tottenham, they sacked Nuno Espirito Santo on Monday and replaced him with one of the world’s best in Antonio Conte.
The appointment is a game changer for FPL and having been a most avoid, some of Spurs’ assets now become most owns.
A trip to Everton is a favourable start given the hosts form and Heung Min Son is someone who could benefit from the change in manager.
Leeds United vs. Leicester City: Jamie Vardy
Having returned just a single point in both of his last two fixtures, Sunday’s trip to Leeds United represents an excellent chance for Jamie Vardy to return his form.
Vardy scored one and assisted another in the fixture last year, a 4-1 win for Leicester City.
Both sides have struggled to replicate last season’s form this time around, but Leicester remain within touching distance of the top four.
An away win looks the bet here and you’d fancy Vardy to get back in the points.
West Ham United vs. Liverpool: Mohamed Salah
Not the easiest game to continue the permanent captaincy for Mohamed Salah; however he has an excellent record against the Hammers.
Salah has nine goals and two assists in just eight league meetings against the Hammers and scored a brace in the fixture last term.
Roberto Firmino suffered an injury in midweek which increases the appeal of the under priced Diogo Jota for an alternative pick.
GW11 Dream Team: Foster; Henry, Chilwell, Rudiger, Livramento; Salah (C), Smith-Rowe, Gallagher, Son; Vardy, Toney
GW10 Dream Team: Foster (2); Alexander-Arnold (1), Cancelo (2), Dias (1), Chilwell (8); Salah (10), Jota (1), Raphinha (9), Son (2); Antonio (2), Hwang (2)