Two of the Italian top three go head to head on Saturday as champions Juventus host the league leaders Inter.
Juve beat the previous leaders Napoli last time out, with Gonzalo Higuain scoring an early winner.
They also progressed into the knock out stages of the Champions League in the week, easing to a 2-0 success at Olympiakos.
Inter have been superb this season under Luciano Spalletti and are unbeaten thus far and they hit Chievo Verona for five last weekend.
The former Manchester United target Ivan Perisic hit a hat-trick in the week as Inter went top.
Serie A form: Juventus W4 D0 L1; Inter W4 D1 L0
Serie A top scorers
Juventus – Paulo Dybala 12 goals
Inter – Mauro Icardi 16 goals
Both teams won the home meeting last season, with Juventus edging to a 1-0 success in front of their own fans.
Last five meetings in all comps (Serie A unless stated)
Juventus 1 Inter 0 – 05/02/17
Inter 2 Juventus 1 – 18/09/16
Inter 3 Juventus 0 (Coppa Italia) – 02/03/16
Juventus 2 Inter 0 – 28/02/16
Juventus 3 Inter 0 (Coppa Italia) – 27/01/16
Under 2.5 goals – 13/14 with 888 Sport
Gianluigi Buffon is a huge doubt for the home side meaning former Arsenal goalkeeper Wojciech Szczesny may deputise.
Mario Mandzukic and Giorgio Chiellini are available for Juventus though having missed the win in Greece.
Miranda and Roberto Gagliardini are set to return having missed the win over Chievo through suspension.
The pressure will be on Inter top scorer Mauro Icardi here and he will lead the line.
Expected starting XI’s
Juventus (4-3-3): Szczesny; De Sciglio, Benatia, Chiellini, Sandro; Marchisio, Khedira, Pjanic; Dybala, Higuain, Mandzukic
Inter (4-2-3-1): Handanovic; D’Ambrosio, Skriniar, Miranda, Santon; Gagliardini, Vecino; Candreva, Valero, Perisic; Icardi
Result: Juventus (4/6 with Bet 365)
Correct Score: 1-0 (13/2 with Betfair)
Anytime Goalscorer: Mario Mandzukic (15/8 with Betfair)