Cristiano Ronaldo returns to Old Trafford on Tuesday evening as Juventus travel to face Manchester United in the Champions League.
Anthony Martial scored twice as United drew 2-2 away at Chelsea on the weekend, conceding a 96th minute equaliser.
They have claimed four points from their first two Champions League games following a goalless draw vs. Valencia last time out.
Juventus dropped points for the first time in all competitions on the weekend, as they were held to a draw at home by Genoa.
Last time out in the Champions League they thrashed Young Boys 4-0, with Paulo Dybala scoring a hat-trick.
Diego Dalot could return to the line-up provided he overcomes a minor injury.
Alexis Sanchez was expected to start here; however was ruled out on Monday by Jose Mourinho.
Giorgio Chiellini and Dybala were among the substitutes on the weekend and both are likely to start at Old Trafford.
Emre Can is an injury doubt and his muscular problem could require surgery.
Expected starting XI’s
Manchester United (4-2-3-1): De Gea; Dalot, Smalling, Lindelof, Shaw; Matic, Pogba; Rashford, Mata, Martial; Lukaku
Juventus (4-3-3): Szczesny; Cancelo, Bonucci, Chiellini, Sandro; Pjanic, Matuidi, Bentancur; Dybala, Mandzukic, Ronaldo
Correct Score: 0-1
Anytime Goalscorer: Mario Mandzukic