The first FA Cup Quarter-Final takes place on Saturday lunchtime as Middlesbrough host Manchester City.
Middlesbrough have been woeful in 2017 domestically and were beaten 2-0 away at Stoke City last time out.
So far in the competition they have been given a favourable run, eliminating Oxford United in the previous round.
In the Fifth Round Manchester City required a replay to get the better of Championship side Huddersfield Town.
The Citizens were held to a goalless draw by Stoke City on Wednesday evening in their re-arranged Premier League fixture.
Form guide: Middlesbrough W1 D1 L3; Manchester City W3 D2 L0
2016/17 top scorers
Middlesbrough – Alvaro Negredo 7 goals
Manchester City – Sergio Aguero 23 goals
Middlesbrough earned a surprise point at the Etihad earlier in the season, thanks to a Martin de Roon injury time strike.
Middlesbrough famously eliminated Manchester City from the 2015 FA Cup, winning 2-0 at the Etihad.
Last five meetings in all comps
Manchester City 1 Middlesbrough 1 – 05/11/16
Manchester City 0 Middlesbrough 2 – 24/01/15
Middlesbrough 0 Manchester City 1 – 02/01/10
Manchester City 1 Middlesbrough 0 – 07/02/09
Middlesbrough 2 Manchester City 0 – 28/10/08
Defensively Middlesbrough will be pushed here, with Bernando set to start with Daniel Ayala and Calum Chambers likely to miss out.
Alvaro Negredo will continue up front against his old side, despite struggling for goals this term.
Manchester City could rotate here slightly with one eye on their Champions League second leg tie with Monaco on Wednesday evening.
Raheem Sterling and David Silva were both rotated against Stoke and could start here.
Expected starting XI’s
Middlesbrough (4-3-3): Guzan; Fabio, Bernando, Gibson, Friend; Leadbitter, De Roon, Forshaw; Traore, Negredo, Fischer
Manchester City (4-2-3-1): Bravo; Zabaleta, Stones, Kompany, Clichy; Fernandinho, Fernando; Navas, Sterling, Silva; Iheanacho
Result: Manchester City (4/9 with Sky Bet)
Correct Score: 0-2 (6/1 with Bet 365)
Anytime Goalscorer: Raheem Sterling (2/1 with Bet 365)