Manchester United take a three goal advantage to France on Wednesday evening in the second leg of their Europa League tie.
A Zlatan Ibrahimovic hat-trick helped United to a rather unconvincing 3-0 success in the first leg at Old Trafford.
Etienne were beaten away at Montpellier on the weekend meaning they are four points adrift of fourth spot.
United edged past Blackburn Rovers in the FA Cup, coming from a goal down to win at Ewood Park and progress into the last eight of the competition.
Enhanced match odds
Manchester United to beat Saint Etienne: 10/1 with Betfair*
Manchester United to beat Saint Etienne: 10/1 with Paddy Power*
Manchester United to beat Saint Etienne to nil: 11/1 with 888 Sport*
Europa League form: Saint Etienne W2 D2 L1; Manchester United W4 D0 L1
Europa League top scorers
Saint Etienne – Robert Beric & Aleksandar Soderlund 2 goals each
Manchester United – Zlatan Ibrahimovic 5 goals
Loic Perrin is a big doubt for Etienne after he missed the weekend loss against Montpellier with concussion.
United are likely to rotate the side here with one eye on the Capital One Cup final on Sunday afternoon.
The likes of Sergio Romero, Ashley Young and Bastian Schweinsteiger are all likely to be given chances.
Expected starting XI’s
Saint Etienne (4-3-3): Ruffier; Malcuit, Perrin, Theophile-Catherine, Pogba; Selnas, Lemoine, Saivet; Hamouma, Beric, Monnet-Paquet
Manchester United (4-2-3-1): Romero; Young, Bailly, Rojo, Blind; Carrick, Schweinsteiger, Pogba; Mata, Rashford, Martial
Result: Draw (12/5 with Bet 365)
Correct Score: 1-1 (6/1 with Paddy Power)
Anytime Goalscorer: Anthony Martial (11/5 with Paddy Power)
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