Real Madrid will look to extend their record unbeaten run in all competitions when they travel to face Sevilla on Sunday evening.
The pair met in the Copa del Rey second leg on Thursday evening, with a 3-3 draw enough for Madrid to progress.
Sevilla moved into second spot in La Liga having thrashed Real Sociedad 4-0 last weekend.
Madrid remain comfortably clear at the top having eased past Granada 5-0, with Isco scoring twice.
La Liga form: Sevilla W4 D0 L1; Real Madrid W4 D1 L0
La Liga top scorers
Sevilla – Wissam Ben Yedder 8 goals
Real Madrid – Cristiano Ronaldo 11 goals
Real Madrid have already eliminated Sevilla from the Copa del Rey this term, including a 3-0 success at the Bernabeu.
Sunday’s meeting will be the fourth between the two this season, after Madrid beat Sevilla in the Super Cup final.
Last five meetings (La Liga unless stated)
Sevilla 3 Real Madrid 3 (Copa del Rey) – 12/01/17
Real Madrid 3 Sevilla 0 (Copa del Rey) – 04/01/17
Real Madrid 3 Sevilla 2 (Super Cup) – 09/08/16
Real Madrid 4 Sevilla 0 – 20/03/16
Sevilla 3 Real Madrid 2 – 08/11/15
Adil Rami is available again for Sevilla following suspension and is likely to return into the heart of their defence.
Gareth Bale is Madrid’s only guaranteed absentee, although Isco, Pepe and James Rodriguez are doubts.
Expected starting XI’s
Sevilla (3-4-3): Rico; Pareja, Mercado, Rami; Mariano, N’Zonzi, Nasri, Escudero; Vazquez, Yedder, Vitolo
Real Madrid (4-3-3): Navas; Carvajal, Ramos, Varane, Marcelo; Kroos, Casemiro, Modric; Vazquez, Benzema, Ronaldo
Result: Draw (3/1 with Sky Bet)
Correct Score: 2-2 (11/1 with Sky Bet)
Anytime Goalscorer: Karim Benzema (13/10 with Paddy Power)