Chelsea will look to record an incredible 14th league win in a row when they travel to White Hart Lane on Wednesday evening.
Tottenham are also in good form and thrashed Watford 4-1 on New Years Day.
Both Harry Kane and Dele Alli scored braces as they won for a fourth consecutive league fixture.
Chelsea were too strong for Stoke City on New Years Eve, winning 4-2 at Stamford Bridge.
Willian scored twice, with Gary Cahill and Diego Costa also finding the net for the hosts.
Enhanced match odds
Premier League form: Tottenham W4 D0 L1; Chelsea W5 D0 L0
Premier League top scorers
Tottenham – Harry Kane 10 goals
Chelsea – Diego Costa 14 goals
The meeting between the pair earlier in the season saw Chelsea recover from a goal down to win 2-1.
Both matches last term finished level, including a goalless draw at the Lane.
Last five Premier League meetings
Chelsea 2 Tottenham 1 – 26/11/16
Chelsea 2 Tottenham 2 – 02/05/16
Tottenham 0 Chelsea 0 – 29/11/15
Tottenham 5 Chelsea 3 – 01/01/15
Chelsea 3 Tottenham 0 – 03/12/14
Spurs will welcome back both Kyle Walker and Toby Alderweireld from suspension here.
Mousa Dembele was a substitute against Watford, but is expected to start against Chelsea.
Marcos Alonso is a doubt for Chelsea, but should be involved, with Chelsea naming a similar XI here.
Pedro returns from a ban, but could be on the bench after Willian’s brace against Stoke.
Expected starting XI’s
Tottenham (4-2-3-1): Lloris; Walker, Alderweireld, Vertonghen, Rose; Wanyama, Dembele; Sissoko, Alli, Eriksen; Kane
Chelsea (3-4-3): Courtois; Azpiliceuta, Luiz, Cahill; Moses, Matic, Kante, Alonso; Willian, Costa, Hazard
Result: Draw (12/5 with Bet 365)
Correct Score: 1-1 (6/1 with Bet Victor)
Anytime Goalscorer: Diego Costa (8/5 with Bet Victor)