Manchester City require just a point to guarantee a Champions League spot away at Watford on Sunday.
Watford were edged out by the champions Chelsea 4-3 in a classic on Monday evening.
Sunday’s fixture will be Walter Mazzarri’s last in charge, with the Italian leaving Watford after one full season.
Manchester City took a giant step towards a top four finish when they beat West Brom comfortably in mid-week.
Kevin de Bruyne was superb, scoring one and assisting another in a 3-1 victory.
Premier League form: Watford W0 D0 L5; Manchester City W3 D2 L0
Premier League top scorers
Watford – Troy Deeney 10 goals
Manchester City – Sergio Aguero 18 goals
The majority of meetings between the pair in recent years have been in the FA Cup and City have an excellent recent record against the Hornets.
City also won earlier in the season between the two teams, easing to a 2-0 success at the Etihad.
Last five meetings
Manchester City 2 Watford 0 – 14/12/16
Watford 1 Manchester City 2 – 02/01/16
Manchester City 2 Watford 0 – 29/08/15
Manchester City 4 Watford 2 – 25/01/14
Manchester City 3 Watford 0 – 05/01/13
Manchester City & BTTS – 7/4 with Stan James
Watford have a defensive crisis and Etienne Capoue is likely to start in central defence with Sebastian Prodl banned.
Troy Deeney is set to start among the subs again, with Stefano Okaka scoring against Chelsea on Monday.
Manchester City have numerous options and Raheem Sterling is set to be on the bench here.
Sergio Aguero has been rotated recently, however is expected to start up front with Gabriel Jesus here.
Expected starting XI’s
Watford (4-5-1): Gomes; Janmaat, Mariappa, Capoue, Holebas; Amrabat, Doucoure, Behrami, Cleverley, Niang; Okaka
Manchester City (4-2-2-2): Caballero; Zabaleta, Kompany, Otamendi, Clichy; Fernandinho, Silva; De Bruyne, Sane; Aguero, Jesus
Result: Manchester City (3/10 with Paddy Power)
Correct Score: 1-3 (21/2 with Bet Victor)
Anytime Goalscorer: Kevin de Bruyne (2/1 with Stan James)