Barcelona need to overturn a huge deficit when they host Paris Saint Germain in the second leg of their Champions League tie.
PSG stunned the La Liga champions in the first leg in France, winning 4-0 producing an amazing performance.
Barcelona have looked good since the defeat and thrashed Celta Vigo on the weekend to remain top of La Liga.
PSG needed a late penalty to overcome Nancy, with Edinson Cavani’s strike meaning they remain three points off Monaco.
Champions League form: Barcelona W3 D0 L2; Paris Saint Germain W3 D2 L0
Champions League top scorers
Barcelona – Lionel Messi 10 goals
PSG – Edinson Cavani 7 goals
Barcelona eased past Paris Saint Germain 5-1 on aggregate on way to the 2015 Champions League title.
The pair have met six times in the competition since 2013, with PSG winning just the once.
Last five Champions League meetings
Paris Saint Germain 4 Barcelona 0 – 14/02/16
Barcelona 2 Paris Saint Germain 0 – 21/04/15
Paris Saint Germain 1 Barcelona 3 – 15/04/15
Barcelona 3 Paris Saint Germain 1 – 10/12/14
Paris Saint Germain 3 Barcelona 2 – 30/09/14
Barcelona -1 handicap: 23/20 with Coral
Barcelona are likely to deploy a back three here, with Rafinha being deployed from a right midfield role.
Angel Di Maria was not risked at the weekend but should be fit enough to start on Wednesday, whilst Thiago Silva is set to return to the team.
Expected starting XI’s
Barcelona (3-4-3): Stegen; Pique, Umtiti, Alba; Rafinha, Busquets, Iniesta, Rakitic; Messi, Suarez, Neymar
Paris Saint Germain (4-3-3): Trapp; Meunier, Marquinhos, Silva, Kurzawa; Verratti, Rabiot, Matuidi; Di Maria, Cavani, Draxler
Result: Barcelona (1/2 with Betfair)
Correct Score: 3-1 (10/1 with Paddy Power)
Anytime Goalscorer: Luis Suarez (8/13 with Paddy Power)