There are around about 15 hours between the conclusion of GW15 and the deadline for GW16 with the Christmas fixtures coming thick and fast.
Having a strong squad is important at this time of the season as rotation is very likely, so having a playing bench could be the difference between a good and bad week.
The stand out fixture of GW16 sees Everton welcome Manchester City to Goodison Park, with the two sides in very good form.
Crystal Palace vs. Leicester City: Harvey Barnes
Crystal Palace will be looking to end a poor run of form when they host Leicester in the first game of the round.
Palace were thrashed again on the weekend, losing 3-0 away at the 10 men of Aston Villa.
Leicester City twice rallied to earn a point with Manchester United, however Brendan Rodgers has admitted he will likely rotate here.
As a result picking players isn’t easy, with Harvey Barnes perhaps the best option, especially if Jamie Vardy is benched.
Chelsea vs. Aston Villa: Mason Mount
Frank Lampard is likely to ring the changes for a second game in three days, especially after such an inept display at Arsenal.
It’s tough to predict who will start for the Blues, however Lampard’s favourite Mason Mount will probably continue.
Aston Villa are enjoying an excellent run of their own and it’d be no surprise if they got a result here.
Everton vs. Manchester City: Kevin de Bruyne
Manchester City aren’t quite firing on all cylinders, however have been defensively excellent in recent weeks, conceding just once in their last six league games.
Kevin de Bruyne is perhaps the only guarantee to remain in the XI with Pep Guardiola claiming the Belgian will be preserved for Premier League matches.
Defensive options include Joao Cancelo who will likely continue with Kyle Walker absent and the in-form Ruben Dias.
Brighton vs. Arsenal: Bukayo Saka
Arsenal earned a much needed win at home to Chelsea on the weekend and will look to back that up at Brighton on Tuesday.
Pierre Emerick Aubameyang is likely to remain on the bench due to injury, meaning the youngster Buyako Saka is a good pick.
Saka scored an excellent goal (if he meant it) in the win over Chelsea and in a poor season for the Gunners, he has been a rare positive.
Burnley vs. Sheffield United: Charlie Taylor
Burnley will look to inflict more pain on rock bottom Sheffield United on Tuesday as they attempt to move away from the bottom three themselves.
Charlie Taylor has been in excellent form for the hosts, returning 19 points in his last four GW’s.
Sheffield United have been desperately poor in front of goal this season and it really wouldn’t be a surprise if the hosts kept a third clean sheet in five.
Southampton vs. West Ham: Che Adams
Southampton will hope to benefit from an extra days rest on opponents West Ham United on Tuesday.
Danny Ings remains a fitness doubt, meaning the pressure will be on his strike partner Che Adams to produce the goods.
Adams has enjoyed a very good campaign and faces a West Ham United defence that hasn’t kept a clean sheet in six matches.
West Brom vs. Leeds United: Semi Ajayi
Semi Ajayi earned West Brom a much needed but very surprising point away to champions Liverpool on Sunday.
Ajayi has been very good for the Baggies this season and will look to cause problems to a Leeds side that struggles from set pieces.
Patrick Bamford’s excellent campaign continued on Sunday with the winner against Burnley and perhaps he is the best shout for the visitors.
Manchester United vs. Wolves: Bruno Fernandes
Bruno Fernandes made his debut for Manchester United against Wolves just shy of a year ago and the Portuguese midfielder has arguably been the best in the Premier League since his arrival.
Fernandes produced another double digit return in the draw with Leicester on Saturday and will fancy his chances of more points here.
Wolves have really struggled for goals in recent weeks and despite United’s inconsistency this season, a home win is the big favourite.
Tottenham vs. Fulham: Harry Kane
Tottenham’s horrible run of fixtures comes to an end on Wednesday when they host Fulham.
Fulham have improved massively in recent weeks and defensively are a completely different side to the one that started the campaign.
Despite that, it’s hard to look past a Spurs win here as they look to end a run of four without a win having been frustrated late on at Wolves.
Harry Kane and Heung Min Son have blanked in three and two consecutive matches respectively, however they will be among the most transferred in players this GW.
Newcastle United vs. Liverpool: Mohamed Salah
Newcastle United could well feel the wrath of Liverpool on Wednesday after the Reds were frustrated at home by West Brom.
Newcastle have been hit by Covid-19 and a mixed run of form and there is pressure on Steve Bruce despite their position of relative safety.
Mohamed Salah produced a rare blank in the draw with WBA and will be desperate to extend his lead at the top of the FPL scoring chart.
GW16 Dream Team: Lloris; Taylor, Robertson, Cancelo; Salah, Son, Fernandes, Mount, Barnes; Adams, Kane
GW15 Dream Team: Martinez (10); Robertson (2), Alexander-Arnold (2), Cancelo (7); De Bruyne (3), Salah (4)(C), Grealish (2), Pulisic (2); Kane, Wood (2) Bamford (8)