Juventus entertain Barcelona on Wednesday evening knowing they require a victory if they are to have a chance of topping the group.
Juventus were surprisingly beaten by Sampdoria on the weekend, as a rotated side went down 3-2 to fall four behind Napoli.
A late Gonzalo Higuain goal earned Juventus a draw in their last Champions League tie away at Sporting Lisbon.
Barcelona played out a drab goalless draw away at Olympiakos in their last European fixture.
They have opened up an 11 point advantage over both Atletico and Real Madrid domestically though, following a 3-0 win at Leganes on Saturday.
Juventus will select the likes of Paulo Dybala and Gianluigi Buffon who were rested vs. Sampdoria on Sunday.
Douglas Costa and Mario Mandzukic will battle it out for the left wing role in the side.
Gerard Pique returns following a European ban and will partner Samuel Umtiti in defence.
Ivan Rakitic could lose his spot in the side to Paulinho who has enjoyed an excellent start to his Barcelona career.
Expected starting XI’s
Juventus (4-2-3-1): Buffon; De Sciglio, Barzagli, Chiellini, Alex Sandro; Pjanic, Matuidi; Cuadrado, Dybala, Costa; Higuain
Barcelona (4-4-2): Ter Stegen; Semedo, Pique, Umtiti, Alba; Alcacer, Paulinho, Busquets, Iniesta; Messi, Suarez
Result: Draw (5/2 with Betfair)
Correct Score: 1-1 (5/1 with Sky Bet)
Anytime Goalscorer: Paulo Dybala (39/19 with 888 Sport)