Tottenham welcome the German side Borussia Dortmund to Wembley for the pair’s first Champions League game of the season.
Spurs eased past Everton on the weekend to get their campaign back on track, winning 3-0 at Goodison Park.
Harry Kane scored his first league goals of the season, with the first of his brace his 100th for the club.
Borussia Dortmund were held to a disappointing draw away at Freiburg on the weekend, with the hosts playing over an hour with 10 men.
Yoric Ravet was dismissed early on, however Dortmund failed to find the break through.
Tottenham will be without Dele Alli for their first three Champions League games following his red card in the Europa League last campaign.
Victor Wanyama is set to miss out again here through injury, meaning Harry Winks could be in line to start.
Moussa Sissoko is a doubt having been forced off versus Everton, whilst Fernando Llorente is still short of fitness.
Dortmund have numerous absentees including Andre Schurrle, Marc Barta, Julian Weigl and Raphael Guerreiro.
Expected starting XI’s
Tottenham (3-5-1-1): Lloris; Sanchez, Alderweireld, Vertonghen; Trippier, Winks, Dier, Dembele, Davies; Eriksen; Kane
Borussia Dortmund (4-3-3): Burki; Piszczek, Toprak, Sokratis, Zagadou; Gotze, Sahin, Castro; Pulisic, Aubameyang, Philipp
Result: Borussia Dortmund (21/10 with Sky Bet)
Correct Score: 1-2 (21/2 with Bet Victor)
Anytime Goalscorer: Pierre Emerick Aubameyang (25/19 with 888 Sport)