Two sides with 100% records from three matches meet at Vicarage Road as Watford host Tottenham.
Watford edged past Crystal Palace last weekend to extend their perfect start to the league season.
Roberto Pereyra scored his third goal of the season, with Jose Holebas also among the scorers.
Tottenham embarrassed Manchester United at Old Trafford, winning 3-0 on Monday evening.
Harry Kane opened the scoring with a superb header, with Lucas Moura scoring a brace in a comfortable win.
Watford have an awful record against Tottenham in the Premier League, claiming just one point from six matches since returning to the division in 2015.
The point did come in the fixture last year, a 1-1 draw, with Heung Min Son equalising for the visitors.
Last five Premier League meetings
Tottenham 2 Watford 0 – 30/04/18
Watford 1 Tottenham 1 – 02/12/17
Tottenham 4 Watford 0 – 08/04/17
Watford 1 Tottenham 4 – 01/01/17
Tottenham 1 Watford 0 – 06/02/16
Watford are unlikely to make changes from the side that beat Crystal Palace.
Gerard Deulofeu could return to the subs bench, however Nathaniel Chalobah remains injured.
Hugo Lloris has been ruled out with a thigh injury, meaning Michel Vorm will deputise.
Ben Davies is likely to replace Danny Rose in the other potential change from the win at Old Trafford.
Expected starting XI’s
Watford (4-4-2): Foster; Janmaat, Catchcart, Kabasele, Holebas; Hughes, Capoue, Doucoure, Pereyra; Gray, Deeney
Tottenham (4-2-3-1): Vorm; Trippier, Alderweireld, Vertonghen, Davies; Dier, Dembele; Lucas, Dele, Eriksen; Kane
Result: Draw (16/5 with Bet 365)
Correct Score: 1-1 (15/2 with Bet Victor)
Anytime Goalscorer: Harry Kane (16/19 with 888 Sport)